VitroGel IKVAV High Concentration
Laminin-derived functional peptide (IKVAV) modified – tunable, xeno-free hydrogel, high concentration (3 mL kit).
VitroGel IKVAV High Concentration is a tunable, xeno-free (animal origin-free) hydrogel system modified with laminin-derived functional peptide (IKVAV). IKVAV is the bioactive sequence located on the C-terminal end of the long arm of the α‐1 chain of laminin, which is actively involved in different biological activities such as neuronal progenitor cell differentiation, promoting cell adhesion, neurite outgrowth, angiogenesis, and tumor growth. VitroGel IKVAV High Concentration comes with VitroGel Dilution Solution to adjust the final hydrogel strength from 10 to 4000 Pa.
VitroGel High Concentration hydrogels are xeno-free, tunable hydrogels for researchers wanting full control to manipulate the biophysical and biological properties of the cell culture environment. The tunability of the hydrogel gives the ability to create an optimized environment for cell growth. The hydrogel system has a neutral pH, transparent, permeable and compatible with different imaging systems. The solution transforms into a hydrogel matrix by simply mixing with the cell culture medium. No cross-linking agent is required. Cells cultured in this system can be easily harvested with VitroGel Cell Recovery Solution. The hydrogel can also be tuned to be injectable for in vivo studies.
From 3D cell culture, 2D cell coating to animal injection, VitroGel makes it possible to bridge the in vitro and in vivo studies with the same platform system.
Mix & Match – 3D Cell Culture Your WAY!
Unique to VitroGel High Concentration hydrogels is the ability to tailor create a multi-functional hydrogel by blending different types of VitroGel. VitroGel IKVAV High Concentration can be “mix & matched” with other VitroGel High Concentration hydrogels such as VitroGel MMP, VitroGel YIGSR, VitroGel RGD, and VitroGel COL to create a customized multi-functional hydrogel. Using this flexible and powerful hydrogel system, scientists customize their 3D culture micro-environment for different applications.
Tunable Hydrogel Strength
Simply diluting the hydrogel controls the gel strength.
|Contents||- VitroGel IKVAV High Concentration, 3 mL
- VitroGel Dilution Solution, 50 mL
|Formulation||Xeno-free tunable hydrogel modified with IKVAV peptide.|
|Use||Support neuronal progenitor cells diferentation, promoting cells adhesion, neurite outgrowth, angiogenesis and tumor growth.|
|Mix & Match||Can be blended with other versions of VitroGel concentrated hydrogels to create a custom multi-functional matrix.|
|Hydrogel Strength||10 to 4,000 Pa of G’ depending on dilution ratio.
Dilute with VitroGel Dilution Solution (TYPE 1 or TYPE 2) for different concentrations.
|Cell Harvesting||VitroGel Organoid Recovery Solution
5-15 min cell recovery
|Storage||Store at 2-8°C. Ships at ambient temperature|
|Number of Uses||Dilution ratio:
1:2 = 225 uses at 50 µL per well
1:3 = 300 uses at 50 µL per well
1:5 = 450 uses at 50 µL per well
3D Cell Culture Process in 20 Minutes
VitroGel High Concentration hydrogels are easy-to-use. There is no cross-linking agent required. Work confidently at room temperature.