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Get rid of freezing conditions and store nucleic acids samples at room temperature with 300K solution adding safety and making your repository more efficient maintaining the same level of sample quality for downstream applications.
Evaluation of the quality and integrity of the purified gDNA performed with Agilent 2200 TapeStation. Same purified DNA is evaluated in fresh and after stabilization and drying with the 300K method. Comparable DIN values are obtained at different time points of long term storage either at room temperature or at accelerated ageing conditions (*).
Single-nucleotide polymorphism (SNP) analysis of the same sample in 3 different conditions: fresh sample at 24 hours (Pink) 300K lyophilized DNA (blue) and DNA sample under a cycle of -80ºC. The results show the same alterations (chromosome 11 shown in the example) are detected in the 3 conditions of DNA storage.
Additional resources:
WP: «DNA Preservation and Storage at Room Temperature»
Video: «Novel Dry Storage Approach for DNA Preservation at Room Temperature»
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